2021 Overview

Competitive Funding for FY 2021 – 2022: 

$ 8,922,527.32

Major Awards Received:

  • UBC Faculty of Medicine 2021 Distinguished Achievement Award – Excellence in Foundational Science Research – Dr. Mark Cembrowski
  • UBC Faculty of Medicine 2021 Distinguished Achievement Award – Excellence in Education – Dr. Karen Pinder
  • UBC Faculty of Medicine 2021 Distinguished Achievement Award – Advancement of Equity, Diversity and Inclusiveness – Dr. Elizabeth Rideout
  • Henry Gray Scientific Achievement from the American Association for Anatomy – Dr. Wayne Vogl
  • UBC Killam Teaching Prize 2020/21- Dr. Olusegun Oyedele
  • Fellow of the American Association for Anatomy – Dr. Claudia Krebs
Other Awards, Research Grants & Funding Received

  • Alzheimer’s Society Research Program. Proof of Concept Grant
  • American Association for Anatomy Innovation Grant
  • Aurinia Research Contract
  • Azrieli Future Leader in Canadian Brain Research
  • Canada Foundation for Innovation (CFI) Grant
  • Canada Foundation for Innovation (CFI) -  John R. Evans Leaders Fund (JELF) Grant
  • Canadian Cancer Society Research Institute (CCSRI) Impact Grant
  • Canadian Foundation for Innovation in Vivo Multimodal Analysis of neuroProjectome (iMAP)
  • Canadian Institutes for Health Sciences (CIHR) Foundation Grant
  • Canadian Institutes of Health Research (CIHR) - Juvenile Diabetes Research Foundation (JDRF) Grant
  • Canadian Institutes of Health Research (CIHR) New Investigator Award
  • Canadian Institutes of Health Research (CIHR) Operating Grant 
  • Canadian Institutes of Health Research (CIHR) Team Grant
  • Canadian Tricouncil New Frontiers in Research Fund
  • CIHR-JDRF Team Grant – 100th Anniversary of Insulin
  • Collaborative Health Research Projects (CHRP) Grant
  • CoVARR-Net Fund
  • Dawn Shaw Alzheimer’s Disease Research Grant
  • Defense Advanced Research Projects Agency (DARPA) Fund
  • Diabetes Canada - Diabetes Investigator Award
  • Fellow of the American Association for Anatomy
  • Genome BC Award
  • Howard Hughes Medical Institute Visiting Scientist Award
  • International Spinal Research Trust Grant
  • JDRF – Centre of Excellence
  • Lustgarten Foundation Grant
  • MDUP Teaching Excellence Award
  • Michael Smith Foundation for Health Research (MSFHR) Scholar Award
  • Mike & Valeria Rosenbloom Foundation Research Award
  • National Institutes of Health (NIH) Grant
  • Natural Sciences and Engineering Research Council (NSERC) Alliance Grant
  • Natural Sciences and Engineering Research Council (NSERC) Discovery Grant
  • NIH /NINDS – Exploratory Neuroscience Research Grant
  • NSERC Alliance COVID-19 Grant
  • Philanthropy Grant
  • Rick Hansen Foundation Fund
  • Simon Foundation Autism Research Initiative
  • Social Sciences and Humanities Research Council (SSHRC) Grant
  • Stem Cell Network Award
  • Terry Fox Research Institute Grant
  • UBC Dentistry Teaching Award 
  • UBC Faculty of Medicine Strategic Investment Fund (SIF)
  • UBC Strategic Investment Fund Teaching Grant
  • UBC Teaching and Learning Enhancement Fund (TLEF)
  • US Department of Defense Convergence Science Research Award
  • US DoD-TRA Fund
  • Wings for Life Fund

Publications

Accili, Eric

E. Accili. An ion channel in the company of a transporter. Journal of General Physiology, 152(7): e202012590, 2020

 

Allan, Douglas

Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K  Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun 11, 2073 (2020). https://doi.org/10.1038/s41467-020-15943-0

Anthony JE Berndt, Katerina M Othonos, Tianshun Lian, Stephane Flibotte, Mo Miao, Shamsuddin A Bhuiyan, Raymond Y Cho, Justin S Fong, Seo Am Hur, Paul Pavlidis, Douglas W Allan (2020) A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons eLife 9:e59650.

 

Bamji, Shernaz

Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K  Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun 11, 2073 (2020). https://doi.org/10.1038/s41467-020-15943-0

 

Cembrowski, Mark

Sullivan, K.E., Kendrick, R.M., Cembrowski, M.S. Elucidating memory in the brain via single-cell transcriptomics. Journal of Neurochemistry, 2020;00:1-11, DOI: 10.1111/jnc.15250

O’Leary, T.P., Sullivan, K.E., Wang, L., Lemire, A., Clements, J., Cembrowski, M.S. Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala. eLife9, e59003:1-27, 2020.

Erwin, S.R., Sun, W., Copeland, M., Lindo, S., Spruston, N., Cembrowski, M.S. A sparse, spatially biased subtype of mature granule cell dominates activity in hippocampal-associated behaviors. Cell Reports31(4): 1-12, 2020.

 

Courneya, Carol-Ann

Courneya, C.A., and Cox, S.M. 2019 Visual Note Taking for Medical Students in the Age of Instagram. Health Professions Education 6(2): 26-135. 

 

Haas, Kurt

Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K  Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun 11, 2073 (2020). https://doi.org/10.1038/s41467-020-15943-0

ChaoJ, Meyers W, Meilli F, MatreyekK, Hollman R, Austin P, Fowler D, Haas K, Roskelley C, Loewen C, (2020) A premalignant cell-based model for functionalization and classification of PTEN variants, Cancer Research. Jul 1;80(13):2775-2789. doi: 10.1158/0008-5472.CAN-19-3278. Epub 2020 May 4. PMID:32366478

Young B, Post K, Chao J, Meili F, Haas K, and Loewen C (2020) Sentinel Interaction Mapping (SIM): A generic approach for the functional analysis of human disease gene variants using yeast. Disease Modeling & Mechanisms.Jul 8;13(7):dmm044560. PMID:32471850

Sakaki K, Podgorski K, Toth TD, Coleman P, and K Haas. (2020). Comprehensive imaging of sensory-evoked activity of entire neurons within the awake developing brain using ultrafast AOD-based random-access two-photon microscopy. Frontiers in Neural Circuits. Jun 16;14:33. doi: 10.3389/fncir.2020.00033. eCollection 2020.PMID:32612514

McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, HendiA, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. (2020) Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A.Jan 7;117(1):656-667. PMID: 31754030

Meili F, Wei WJ, Sin WC, Meyers WM, Dascalu I, Callaghan DB, Rogic S, Pavlidis P, and K Haas. (2020). Multi-parametric analysis of 57 SYNGAP1 variants reveal impacts on GTPase signaling, localization, and protein stability. American Journal of Human Genetics. Dec. 11: DOI:https://doi.org/10.1016/j.ajhg.2020.11.011

 

Johnson, James

Ludwig DS, Ebbeling CB, Bikman BT, Johnson JD. 2020. Testing the Carbohydrate-Insulin Model in Mice: The Importance of Distinguishing Primary Hyperinsulinemia from Insulin Resistance and Metabolic Dysfunction. Molecular Metabolism. Epub. Feb 12. IF6.8/C1 

Phipps SM, Garry CE, Kamal S, Johnson JD, Gilmer J, Long A, Kelleher D, Duggan SP. 2020. High Content Imaging of Barrett’s-Associated High Grade Dysplasia Cells Following siRNA Library Screening Reveals Acid Responsive Regulators of Cellular Transitions. Cellular and Molecular Gastroenterology and Hepatology, 10(3):601-622. IF6.8/C1 

Horianopoulos LC, Hu G, Caza M, Schmitt K, Overby P, Johnson JD, Valerius O, Braus GH, Kronstad JW. 2020. The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans. mBio, 11(3):e01127-20. doi: 10.1128/mBio.01127-20. IF6.784 

Ramzy A, Tudurí E, Glavas MM, Baker RK, Mojibian M, Fox JK, O'Dwyer SM, Dai D, Hu X, Denroche HC, Edeer N, Gray SL, Verchere CB, Johnson JD, Kieffer TJ. 2020. AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. Sci Rep, 10(1):10518. doi: 10.1038/s41598-020-67136-w. IF3.998. 

Lee J, Kim K, Cho JH, Bae JY, O’Leary TP, Johnson JD, Bae YC, Kim, E-K. 2020. Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production. JCI Insight, 5(16). IF6.2/C1 

Botezelli JD, Overby P, Lindo L, Wang S, Haïda O, Lim GE, Templeman NM, Pauli JR, Johnson JD. 2020. Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice. American Journal of Physiology-Endocrinology and Metabolism 2020 319:3, E529-E539

Jara MA, Werneck-de-Castro JP, Lubaczeuski C, Johnson JD, Bernal-Mizrachi E. 2020. Pancreatic and duodenal homeobox-1 (PDX1) mediates β-cell mass expansion and proliferation induced by Akt/PKB pathway. Islets, 12(2), 32-40. IF2.5 

Kolic J, Beet L, Overby P, Cen HH, Panzhinskiy E, Ure DR, Cross JL, Huizinga RB, Johnson JD.  2020. Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. Endocrinology, 161(11). IF4.0 

Yong J, Johnson JD, Han J, Kaufman RJ. Therapeutic opportunities around pancreatic β-cell ER stress in diabetes. Nat Rev Endocrinol 17, 455–467 (2021). https://doi.org/10.1038/s41574-021-00510-4

 

Kieffer, Timothy

Pereira S, Cline DL, Glavas MM, Covey SD,Kieffer TJ. Tissue-specific effects of leptin on glucose and lipid metabolism. Endocrine Reviews, Volume 42, Issue 1, February 2021, Pages 1–28, https://doi.org/10.1210/endrev/bnaa027

Ramzy A, Tudurí E, Glavas MM, Baker RK, Mojibian M, Fox JK, O'Dwyer SM, Dai D, Hu X, Denroche HC, Edeer N, Gray SL, Verchere CB, Johnson JD, Kieffer TJ. 2020. AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. Sci Rep, 10(1):10518. doi: 10.1038/s41598-020-67136-w. IF3.998. 

Ramzy A, Asadi A,Kieffer TJ. Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3but Not PC2.Diabetes.2020 Jul;69(7):1451-1462.4.

Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG,Kieffer TJ, Banks K, Pessin JE, Gaisano HY. SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.JCI Insight.2020 Feb 13;5(3):e129694.

 

Kopp. Janel

Espinet E., Gu Z., Imbusch C.D., Giese N.A., Buscher M., Safavi M., Weisenburger S., Klein C., Vogel V., Falcone M., Insua-Rodriguez J., Reitberger M., Thiel V., Kossi S.O., Muckenhuber A., Sarai K.*, Lee A.Y.*, Backx E., Zarei S.*, Gaida M.M., Rodriguez-Paredes M., Donato E., Yen H.Y., Eils R., Schlesner M., Pfarr N., Hackert T., Plass C., Brors B., Steiger K., Weichenhan D., Arda H.E., Rooman I., Kopp J.L., Strobel O., Weichert W., Sprick M.R., Trumpp A. Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. Cancer Discov. 2020 Oct 15:CD-20-1202. doi: 10.1158/2159-8290.CD-20-1202. 

Ye, J., Huang, A., Wang, H., Zhang, A.N.Y., Huang, X., Lan, Q, Sato, T., Goyama, G., Kurokawa, M., Deng, C., Sander, M., Schaeffer, DFS, Li., W., Kopp, J.L., Xie, R. PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death Dis 11, 187 (2020). https://doi.org/10.1038/s41419-020-2371-x

 

Krebs, Claudia

Pennefather, P., Krebs, C., & Saroyan, J. (2020). Reimagining the Audience-Dancer Relationship Through Mobile Augmented Reality. In C. Soares, & E. Simão (Ed.), Multidisciplinary Perspectives on New Media Art (pp. 119-141). IGI Global. https://doi.org/10.4018/978-1-7998-3669-8.ch006

 

Loewen, Christopher

Shin, J.J.H., Liu, P., Chan, L.J., Ullah, A., Pan, J., Borchers, C.H., Burke, J.E., Stefan, C., Smits, G.J., and Loewen, C.J.R. (2020). pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Developmental Cell, Volume 52, Issue 4, 2020, Pages 461-476.e4, ISSN 1534-5807, https://doi.org/10.1016/j.devcel.2019.12.010.

Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K  Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun 11, 2073 (2020). https://doi.org/10.1038/s41467-020-15943-0

ChaoJ, Meyers W, Meilli F, MatreyekK, Hollman R, Austin P, Fowler D, Haas K, Roskelley C, Loewen C, (2020) A premalignant cell-based model for functionalization and classification of PTEN variants, Cancer Research. Jul 1;80(13):2775-2789. doi: 10.1158/0008-5472.CAN-19-3278. Epub 2020 May 4. PMID:32366478

Young B, Post K, Chao J, Meili F, Haas K, and Loewen C(2020) Sentinel Interaction Mapping (SIM): A generic approach for the functional analysis of human disease gene variants using yeast. Disease Modeling & Mechanisms.Jul 8;13(7):dmm044560. PMID:32471850

 

Moore, Edwin

David R. Scriven, Anne Berit Johnsen, Parisa Asghari, Keng Chang Chou, Edwin D. Moore. Direct Visualization of Type 2 Ryanodine Receptors using dSTORM. Biophysical Journal, vol. 118, issue 3, p. 98a Pub Date: February 2020 DOI: 10.1016/j.bpj.2019.11.697

Parisa Asghari, David RL Scriven, Myles Ng, Pankaj Panwar, Keng C Chou, Filip van Petegem, Edwin DW Moore (2020) Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification eLife 9:e51602. https://doi.org/10.7554/eLife.51602

 

Moukhles, Hakima

Noel G, Tham DKL, MacVicar BA, Moukhles  H. 2020. Agrin plays a major role in the coalescence of the aquaporin-clusters induced by gamma-1-containing laminin. J Comp Neurol. 2020 Feb 15;528(3):407-418.  

Geoffroy Noel Daniel Kai Long Tham , Eric Guadagno , Brian MacVicar , Hakima Moukhles . 2020. The Laminin-Induced Phosphorylation of PKCδ Regulates AQP4 Distribution and Water Permeability in Rat Astrocytes. Cell Mol Neurobiol, 2020 Aug 26. 

 

Nabi, Ivan Robert

Long RKM, Moriarty KP, Cardoen B, Gao G, Vogl AW, Jean F, Hamarneh G, Nabi IR. Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum. Sci Rep. 2020 Dec 1;10(1):20937. doi: 10.1038/s41598-020-77170-3. 

Khater IM, Nabi IR, Hamarneh G. Super-resolution Single Molecule Localization Microscopy Cluster Analysis and Quantification Methods. Patterns. 2020 Jun 12;1(3):100038. doi: 10.1016/j.patter.2020.100038. eCollection 2020 Jun 12 

Nabi IR. Biography – Ivan Robert Nabi. Cancer Metastasis Rev. 2020 Jun;39(2):333. doi: 10.1007/s10555-020-09893-8.PMID: 32577925.

Wong TH, Dickson FH, Timmins LR, Nabi IR. Tyrosine phosphorylation of tumor cell caveolin-1: impact on cancer progression. Cancer Metastasis Rev. 2020 Jun;39(2):455-469. doi: 10.1007/s10555-020-09892-9.PMID: 32440845

Nabi IR. Preface. Cancer Metastasis Rev 39, 335 (2020). https://doi.org/10.1007/s10555-020-09894-7

Indira Chandran V, Mansson AS, Barbachowska M, Cerezo-Magana M, Nodin B, Joshi B, Koppada N, Saad OM, Gluz O, Isaksson K, Borgquist S, Jirstrom K, Nabi IR, Jernstrom H, Belting M. Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity Through Redistribution of Phosphorylated Caveolin-1.  Mol Cancer Res (2020) 18 (4): 644–656. https://doi.org/10.1158/1541-7786.MCR-19-0856

 

O'Connor, Timothy

Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K  Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun 11, 2073 (2020). https://doi.org/10.1038/s41467-020-15943-0

 

Roskelley, Calvin

Dong Y, Arif AA, Guo J, Ha Z, Lee-Sayer, SSM, Poon GFT, Dosanjh M, Roskelley CD, Huan T, Johnson P (2020) CD44 loss disrupts lung lipid surfactant homeostasis and exacerbates oxidized lipid-induced lung inflammation, Front. Immunol., 30 January 2020 Sec. Inflammation https://doi.org/10.3389/fimmu.2020.00029

Hughes MR, Canals Hernaez D, Cait J, Rafaeli I, Lo BC, Roskelley CD, McNagny K (2020) A sticky wicket: Defining molecular functions for CD34 in hematopoietic cells. Experimental Hematology, Volume 86, 2020, Pages 1-14, ISSN 0301-472X, https://doi.org/10.1016/j.exphem.2020.05.004.

Refaeli I, Hughes MR, Wong AK, Bissonette MLZ, Roskelley CD, Vogl AW, Barbour SJ, Freeman BS, McNagny KM (2020) Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. Sci Rep 10, 9419 (2020). https://doi.org/10.1038/s41598-020-64907-3

Chao, JT, Hollman R, Meyers W, Meilli F, Matreyek KA, Austin P, Fowler DM, Haas K, Roskelley CD, Loewen CJR (2020). A premalignant cell-based model for functionalization and classification of PTEN variants. Cancer Research, 80(13): 2775-2789.

 

Tanentzapf, Guy

Khadilkar R.J., Ho K.Y.L., Venkatesh B. & Tanentzapf G., Integrins modulate extracellular matrix organization to control cell signalling during hematopoiesis. Current Biology(2020), 30(17):3316-3329.e5. doi: 10.1016/j.cub.2020.06.027.

Haage A., Wagner K., Mitchell C., Goodwin G.J., Bogutz A., Lefebvre L., Van Raamsdonk C.D., Tanentzapf G. Precise Coordination of Cell-ECM Adhesion is Essential for Efficient Melanoblast Migration During Development. Development. (2020), 147(14):dev184234. doi: 10.1242/dev.184234.

 

Underhill. Michael

Soliman, H., Paylor, B., Scott, R.W., Lemos, D.R., Chang, C-K., Arostegui, M., Low, M., Lee, C., Fiore, D., Braghetta, P., Pospichalova, V., Barkauskas, C., Korinek, V., Rampazzo, A., MacLeod, K., Underhill, T.M. and Rossi, F.M. (2020) Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors. Cell Stem Cell, Volume 26, Issue 2, 2020, Pages 205-220.e8, ISSN 1934-5909, https://doi.org/10.1016/j.stem.2019.12.008.

Hassan, H.M., Isovic, M., Kolendowski, B., Bauer-Maison, N., Onabote, O., Cecchini, M., Vareki, S.M., Underhill, T.M. and Torchia, J. Loss of thymine DNA glycosylase causes dysregulation of bile acid homeostasis and hepatocellular carcinoma. Cell Reports, Volume 31, Issue 1, 2020, 107475, ISSN 2211-1247, https://doi.org/10.1016/j.celrep.2020.03.039.

Uchida, A., Sakib, S., Labit, E., Abbasi, S., Scott, R.W., Underhill, T.M., Biernaskie, J., and Dobrinski, I. (2020) Development and function of smooth muscle cells is modulated by Hic1 in mouse testis. Development (2020) 147 (13): dev185884. https://doi.org/10.1242/dev.185884

Abbasi, S., Sinha, S., Shah, P., Rosin, N., Hagner, A., Islam, A., Chang, C-K., Stratton, J., Scott, R.W., Rossi, F.M., Underhill, T.M. and Biernaskie, J. (2020) Distinct regulatory programs control the latent regenerative potential of dermal fibroblasts during wound healing. Cell Stem Cell, Volume 27, Issue 3, 2020, Pages 396-412.e6, ISSN 1934-5909, https://doi.org/10.1016/j.stem.2020.07.008.

Shin, S.B., Lo, B.C., Ghaedi, M., Scott, R.W., Li, Y., Messing, M., Hernaez, D.C., Cait, J., Murakami, T., Hughes, M.R., Leslie, K.B, Underhill, T.M., Takei, F. and McNagny, K.M. (2020) Abortive gdTCR rearrangements suggest ILC2s are derived from T-cell precursors. Blood Adv 2020; 4 (21): 5362–5372. doi: https://doi.org/10.1182/bloodadvances.2020002758

Hassan, H.M., Isovic, M., Underhill, M.T. and Torchia, J. (2020) TDG is a novel tumor suppressor of liver malignancies. Molecular & Cellular Oncology, 7:4, DOI: 10.1080/23723556.2020.1768819

Arostegui, M. and Underhill, T.M. (2021) Murine limb bud organ cultures for studying musculoskeletal development.  Methods Mol. Biol. 2230:115-137 DOI: 10.1007/978-1-0716-1028-2_8

 

Viau, Victor

Toews JNC, Hammond GL, Viau V(2020) Liver at the nexus of rat postnatal HPA axis maturation and sexual dimorphism. Journal of Endocrinology 248: R1-R17. SA (IF 4.04) DOI: https://doi.org/10.1530/JOE-20-0286

 

Vogl, Wayne

Dhanda, A.S., Yu, C., Lulic, K.T., Vogl, A.W., Rauch, V., Yang, D., Nichols, B.J., Kim, S.H., Polo, S., Hansen C.G. and Guttman, J.A. Listeria monocytogenes exploits host caveolin for cell-to-cell spreading. mBio 11:e02857-19. (2020) https://doi.org/10.1128/mBio.o287-19. 

Refaeli, I., Hughes, M.R., Wong, A., Bissonnette, M.L.Z., Vogl, A.W., Barbour, S.J., Yip, W., Freedman, B.S., McNagny,K.M. Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. Scientific Reports 10:9419  https://doi.org/10.1038/s41598-020-64907-3 (2020). 

Adams, A., Vogl, A.W., Dawson, C., Raverty, S., Haulena, M., and Skoretz, S.A. The anatomical basis for the larynx and soft palate functioning as valves in the harbor seal (Phoca vitulina).  J Exp Biol. 2020 Oct 18;223(Pt 20):jeb230201. doi: 10.1242/jeb.230201. PMID: 32895326.

Gil, K.N., Lillie, M.A., Vogl, A.W. and Shadwick, R.E. Rorqual nasal plugs: protecting the respiratory tract against water entry and barotrauma. J Exp Biol. 2020 Feb 17;223(Pt 4):jeb219691. doi: 10.1242/jeb.219691. PMID: 31974219.

Yang, H., Mirsepasi-Laruidsen, H.C., Struve, C., Allaire, J.M., Sivignon, A., Vogl, W., Bosman, E.S., Ma, C., Fotovati, A., Reid, G.S. Li, X, Petersen, A.M. Gouin, S.G. Barnich, N., Jacobson, K., Yu, H.B. Krogfelt, K.A. and Vallance, B.A. Ulcerative colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts. Gut Microbes. 2020 Nov 9;12(1):1847976. doi: 10.1080/19490976.2020.1847976. Epub 2020 Dec 1. PMID: 33258388; PMCID: PMC7781664.

Adams, A. and Vogl, W. Knockdown of ITPR1 (IP3R-1) disrupts ER-TBC contact sites and the morphology of apical processes encapsulating late spermatids. Biology of Reproduction, Volume 103, Issue 3, September 2020, Pages 669–680, https://doi.org/10.1093/biolre/ioaa074

Morell, M., Vogl, A.W., IJsseldijk L.L., Piscitelli-Doshkov, M., Tong, L., Ostertag, S., Ferreira, M., Fraija-Fernandez, N., Colegrove, K.M., Puel, J., Raverty, S.A. and Shadwick, R.E.  Echolocating whales and bats express the motor protein prestin in the inner ear. Frontiers in Veterinary Science Vol 7, 2020 DOI=10.3389/fvets.2020.00429 ISSN=2297-1769 

Long RKM, Moriarty KP, Cardoen B, Gao G, Vogl AW, Jean F, Hamarneh G, Nabi IR. Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum. Sci Rep. 2020 Dec 1;10(1):20937. doi: 10.1038/s41598-020-77170-3. 

Adams, A. and Vogl, A.W. ORP9 knockdown delays the maturation of TBC bulbs and leads to impaired sperm release.  Biol Reprod. 2020 Dec 1;103(6):1314-1323. doi: 10.1093/biolre/ioaa159. PMID: 32901807.

 

West, Christopher

Hoekstra F, McBride CB, Borisoff J, Fetterly MJ, Ginis S, Latimer-Cheung AE, Ma JK, Maffin J, Mah L, West CR, Williams R, Martin Ginis KA. (2020) Translating the international scientific spinal cord injury exercise guidelines into community and clinical practice guidelines: a Canadian evidence-informed resource. Spinal Cord 58, 647–657 (2020). https://doi.org/10.1038/s41393-019-0410-1

Martin-Ginis KA, van der Scheer J, Todd K, Davis J, Hoekstra F, Gaudet S, Karim M, Kramer J,  Little J, Singer J, Townson A, West CR (2020) Pragmatic Randomized Controlled Trial Testing the Effects of the International Scientific SCI Exercise Guidelines on SCI Chronic Pain: Protocol for the EPIC-SCI Trial. Spinal Cord 58, 746–754 (2020). https://doi.org/10.1038/s41393-020-0478-7

Martin-Ginis KA & West CR (2020) From guidelines to practice: development and implementation of disability-specific physical activity guidelines. Disability and Rehabilitation, 43:24, 3432-3439, DOI: 10.1080/09638288.2020.1757167

Williams AM, Manouchehri N, Erskine E, Tauh K, So K, Shortt K, Webster M, Fisk S, Billingsley A, Munro A, Tigchelaar S, Streijger F, Kyoung-Tae K, Kwon BK. West CR. (2020) Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury. Nat Commun 11, 5209 (2020). https://doi.org/10.1038/s41467-020-18905-8