| CAPS 200 – Biomedical Research: Essential Skills and Concepts (3 credits) Not offered in winter 2020 | Analysis of the underlying questions and assumptions, experimental approach, results and significance of work described in selected biomedical research presentations. |
| Term II Prerequisite: BIOL 200. This course is designed for students in second year. Upper level students are not admitted. Lectures and Labs : Tuesday and Thursday, 12:30 PM to 2:00 PM Location: LSC 1.1416 Course Coordinator: Dr. Sally Osborne Telephone : 1.604.822.3421 Email: sally.osborne@ubc.ca Syllabus About Schedule Course Description: This challenging elective course is designed to transform your understanding of scientific research and the underlying process that allows us to create new knowledge. We will deconstruct 2 research seminars given in class by CPS research scientists.This class uses a flipped-participatory discussion model. You will be guided to think critically and creatively using mini journals, problem sets, seminar summaries and online resources related to the seminar topics. You will have didactic lessons on researching scientific literature using the UBC library e-tools, giving scientific talks and preparing brief research proposals. In lieu of a final examination, you will be expected to craft a research proposal based on one of the seminar speaker’s topics and present it to the class and research scientists. |
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| CAPS 301 – Human Physiology Terms I and II (6 credits) Offered online in winter 2020 | A lecture course on body function with particular reference to mammalian and human physiology. |
| STUDENTS MUST COMPLETE BOTH TERMS 1 & 2 DURING THE SAME ACADEMIC YEAR Prerequisites: BIOL 112, BIOL 121 and one of MATH 101, MATH 103, MATH 105, MATH 121 and one of PHYS 100, PHYS 101, PHYS 107 and one of CHEM 203, CHEM 233, CHEM 260.Lectures: Monday, Wednesday, and Friday 11:00 AM to 12:00 PM. Location: IRC 2Course Coordinator: Dr. Barry Mason Telephone:604-822-7253 Email: barry.mason@ubc.ca Schedule/ Course Info Required Textbook: Human Physiology, From Cells to Systems; Lauralee Sherwood & Christopher Ward. 3rd Canadian Edition, 2016, Nelson Number of Lectures: 72 One-hour lecturesCourse Description: Organ systems function with particular reference to mammalian and human physiology. |
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| Topics Covered: Neurophysiology CNS Muscle Body Fluids Blood |
Cardiovascular Physiology Pulmonary Physiology (Osborne) Renal Physiology – Concentration & Dilution of Urine Gastrointestinal Physiology Endocrinology Reproductive Physiology |
| CAPS 303 – Human Physiology Laboratory: Honours (3 credits) Offered online in winter 2020 | Techniques and principle of human physiology. Restricted to students in CAPS & Pharmacology Honours. |
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Terms I and II Restricted to students in Honours Cellular, Anatomical, and Physiological Sciences and students in Honours Pharmacology. Offered online synchronous mode: Thursdays 2-5 pm PST Course Coordinator: Dr. Sally Osborne
Laboratory sessions in human physiology designed to provide enriched learning aligned with lectures in CAPS 301. All labs involve synchronous class interaction, video demonstration, data analysis, group discussion, and in class assignments. In addition, students are required to complete asynchronous lessons and assignments on reflexes; compound action potential; skeletal muscle structure, EMG and muscular conditions; blood; heart valves, cardiac cycle, cardiac axis, blood pressure regulation; lung anatomy and airflow; kidney anatomy, glomerular & tubular function, fluid & electrolyte balance, urine and micturitions |
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| TERM I
Orientation: Faculty & research in CPS
Introduction to Lt & Stroop Test
Sensory Physiology
Reflexes & Reaction Times
Peripheral Nerve Function
Muscle and EMG
Neuroanatomy
Heart Sounds
Group Project Proposal
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TERM II
Heart and ECG
Blood Pressure
Lung Volumes & Spirometry
Cardiorespiratory effects of Exercise
Energy Expenditure and Exercise
The Kidney and Urine
Glucose Absorption
Project Report
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| CAPS 390 – Introduction to Microscopic Human Anatomy (3 credits) Offered online in winter 2020 |
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| Instructor: Dr. Guy Tanentzapf and Dr.Tim O’Connor Prerequisite: one of the following courses: BIOL 121 – Genetics, Evolution & Ecology SCIE 001 – Science I Program BIOL 200 – Cell Biology I: Structural Basis (recommended) Download CAPS 390 Syllabus 2019 |
| CAPS 391 – Introduction to Gross Human Anatomy (3 credits) | Structure and function of body regions at the macroscopic level. |
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Term II (Winter) January to AprilPrerequisite: Six credits of lower level biology courses. Lectures and Labs: Monday, Wednesday, and Friday 10:00 AM to 11:00 AM. Instructor: Dr. Majid Alimohammadi |
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| CAPS 421 – Advanced Cellular & Molecular Physiology (3 credits) Offered online in winter 2020 | Recent advancements in cellular and molecular physiology that have revolutionized our understanding of cell function in health and disease. |
| Lectures: Monday & Wednesday 2:00-4:00 pm, September – December Course Coordinators: Dr. I. Robert Nabi & Dr. T. Michael Underhill Emails: Ivan.robert.nabi@ubc.ca; tunderhi@brc.ubc.caSyllabus/Outline |
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| CAPS 422 – Mammalian Cardiovascular & Respiratory Physiology (3 credits) Offered online in winter 2020 | The control and integration of cardiopulmonary function in mammals. |
| Lectures: Tuesday & Thursday 8:00-10:00 am, September – December Course Coordinators: Dr. Sally Osborne and Dr. Ed Moore Email: sally.osborne@ubc.ca/edmoore@mail.ubc.ca Schedule REVIEW ARTICLE ECC ARTICLE ECG’s and Arrhythmia handout |
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| CAPS 423 – Mammalian Renal & Gastrointestinal Physiology (3 credits) Offered online in winter 2020 | Control of mammalian renal and gastrointestinal systems. |
| Term I Prerequiste: A cumulative average of 75% over at least 90 credits attempted in the first three years of a student’s program and a minimum mark of 75% in CAPS 301 or PHYL 301. Permission of the course director is also required. Lectures: Tuesday & Thursday 2:00-4:00 pm Course Coordinator: Eric Accili, PhD Office: Rm.3013 DH Copp Bldg, 2146 Health Sciences Mall Telephone: 604-822-6228 Email: Eric.@accili@ubc.ca Schedule / Course Info Background Reading: Selective Chapters of various textbook, Reviews and Journal articles. Number of lectures: 23 two-hour lectures. |
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| RENAL SECTION Functional Anatomy and Circulation of the Kidney Glomerular Filtration and Urinary Excretion Renal Transports Acid base balance Fluid Compartments Water Homeostasis The Urinary Bladder |
GASTROINTESTINAL SECTION GI Tract Overview GI Endocrinology GI Innervation and Taste Perception GI Innervation and Motility Gastric Secretion The Exocrine Pancreas |
| CAPS 424 – Mammalian Endocrinology (3 credits) | Hormonal control of homeostatic, metabolic and reproductive function. |
| January – April Lectures: Tuesday, Thursday 2:00 PM to 4:00 PM Location: LSC 1510 Prerequisite: A cumulative average of 75% over at least 90 credits attempted in the first three years of a student’s program and a minimum mark of 75% in CAPS 301 or its equivalent. Permission of the course director is also required for all except Honours CAPS students. Course Coordinator: TBA Office: Rm. 5352 Life Sciences Mall, 2350 Health Sciences Mall Telephone: 1.604.827.4271 Email: TBA Course Schedule Number of Lectures: 26 Required Textbook: None |
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| This course is intended for Honours students in Physiology or other life sciences. This course is eligible for Credit/D/Fail grading. You must register in the course before you can select the Credit/D/Fail grading option. Registered students will have access to a CAPS 424 web site on UBC Connect as of January 1 preceding the course. This is used for the posting of lecture notes and other relevant course material. In addition to attending lectures, students will also participate in group-based mini-presentations of selected topics. Course Assessment is based on mid-term and final examinations (90%) as well as the student presentations (10%). Examinations are based upon lecture material only. There are no recommended textbooks for the course. |
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| TOPICS Introduction; Peptide hormone biosynthesis/processing; Receptors; Intracellular Signalling Pathways 1 & 2; Endocrine control of transcription and development; Pancreas I & II & III; Adipose tissue and Adipokines I; Regulation of energy balance & body weight; Adipokines II |
Adrenal and the SNS; Hypothalamus/pituitary; Opioid peptides; Downstream effectors of signalling pathways I & II; Reproductive endocrinology I & II & III; Endocrinology in the news |
| CAPS 426 – Physiological Basis of Central Nervous System Functions (3 credits) | An integrated study of the structural and functional organization of the central nervous system with special emphasis on neurophysiological mechanisms. |
| January – April Lectures: Tuesday, Thursday 8:00-10:00am (LSC 1510) Course Coordinator: Dr. Kurt Haas Office: BRC Room F162, Tel: 604-822-9770 Email: kurt.haas@ubc.ca Course Schedule and Topics Prerequisites: CAPS 301. Permission from the Department Head is also required. |
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| CAPS 430 – Advanced Laboratory in Physiology (6 credits) Offered online in winter 2020 | A laboratory course giving training in the methods, techniques and use of instruments required for physiological investigation. |
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Term I & II Prerequisite: CAPS 303 or PHYL 303 and the consent of the department are required and enrollment will be limited. Laboratories: Fridays 10:00 am – 5:00 pm Course Coordinator: Dr. Douglas Allan This is a Laboratory Course for 4th Year Honours Physiology Students* Number of Labs: 24 Description: For the 2020/21 Winter session, all labs will be online and available asynchronously if you require. Labs will include a mix of pre-lab preparation, video demonstrations and lectures, online exercises and class interactions, and instructor-led bioinformatics / computational biology training. Labs are designed to expand learning provided in CAPS 400 level courses and provide practical training in a number of human and animal-based techniques discussed in these courses. Labs include: Human gross anatomy, physiology and human case reports for major organ systems. Electrophysiology. Colorometric assays for metabolic state. Imaging of cellular dynamics. Site directed mutagenesis and Gateway cloning. The use of model invertebrate organisms in biomedical research including genetic interaction screening and assaying the function of human disease variants (which you will publish as original work). Basic training in the use of bioinformatics and R, which is now essential in biomedical sciences, is integrated through many of our labs. |
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| TOPICS – Term I Bioassay for blood pressure I (Baimbridge)Bioassay for blood pressure II (Baimbridge)Bioassay for blood pressure III (Baimbridge)Bioinformatics (Clee, Tanentzapf)Single cell electroporation (Haas)3-D Imaging of electroporated neurons (Haas)Human respiratory function (Osborne)RFLP/SNPs (Hammond)Bioinformatic analysis of synthetic genetic array data (Loewen)pH regulation of lipid metabolism (Loewen)Hypothesis, rationale and experimental planning (Allan)Immunohistochemistry techniques (Kieffer) |
TOPICS – Term II Insulin I: Glucose Regulation of Insulin Expression (Kieffer)Insulin II: OGTT (Kieffer)Insulin III: ELISA (Kieffer)Hypothesis, rationale and experimental planning (Allan)Live Cell Ca2+ Imaging (Johnson)Insulin IV: Viral Transfection (Kieffer)Electrophysiology introduction (Mason)Intracellular Recordings I (Mason)Intracellular Recordings II (Mason)Two-Electrode Voltage Clamp (Ahern)Drug block of ion channels (Kurata) |
| CAPS 448 – Directed Studies in Physiology (3-6 credits) | |
| Course Director: Dr. Guy Tanentzapf, (guy.tanentzapf@ubc.ca) Description & Application |
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| CAPS 449 – Graduating Essay (6 credits) | A two term research project with a Department faculty member, culminating in a written thesis and an oral presentation to faculty. |
| Contact: Dr. Chris Loewen, Rm 2403 Life Sciences Center | |