CAPS Undergraduate Courses – Fall/Winter

CAPS 200 – Biomedical Research: Essential Skills and Concepts (3 credits) Analysis of the underlying questions and assumptions, experimental approach, results and significance of work described in selected biomedical research presentations.
Term II
Prerequisite: BIOL 200. This course is designed for students in second year. Upper level students are not admitted.
Lectures and Labs : Tuesday and Thursday, 12:30 PM to 2:00 PM
Location: Copp Building 3602 (Lectures) and LSC 1.1410 (Lab)
Course Coordinator: Dr. Sally Osborne
Telephone : 1.604.822.3421
Email: sally.osborne@ubc.ca
Course Information: All course information is available online at UBC Connect.
Schedule
Number of Lectures: 26 1.5-hour lectures
Course Description: This challenging elective course is designed to transform your understanding of scientific research and the underlying process that allows us to create new knowledge. We will deconstruct 2  research seminars given in class by CPS research scientists.This class uses a flipped-participatory discussion model.  You will be guided to think critically and creatively using mini journals, problem sets, seminar summaries and online resources related to the seminar topics. You will have didactic lessons on researching scientific literature using the UBC library e-tools, giving scientific talks and preparing brief research proposals.  In lieu of a final examination, you will be expected to craft a research proposal based on one of the seminar speaker’s topics and present it to the class and research scientists.
CAPS 301 – Human Physiology  Terms I and II (6 credits) A lecture course on body function with particular reference to mammalian and human physiology.

MUST COMPLETE BOTH TERM 1 & 2 during the same academic year

Prerequisites: BIOL 112, BIOL 121 and one of MATH 101, MATH 103, MATH 105, MATH 121 and one of PHYS 100, PHYS 101, PHYS 107 and one of CHEM 203, CHEM 233, CHEM 260.

Lectures: Monday, Wednesday, and Friday 11:00 AM to 12:00 PM.
Location: IRC 2

Course Coordinator:  Kenny Kwok, PhD
Office: Rm.3013 DH Copp Bldg, 2146 Health Sciences Mall
Telephone:1.604.822.6228
Email: kenny.kwok@ubc.ca

Schedule/ Course Info
Required Textbook:    Human Physiology, From Cells to Systems; Lauralee Sherwood & Christopher Ward. 3rd Canadian Edition, 2016, Nelson
Number of Lectures: 72 One-hour lectures

Course Description: Organ systems function with particular reference to mammalian and human physiology.

Topics Covered:
Neurophysiology
CNS
Muscle
Body Fluids
Blood
Cardiovascular Physiology
Pulmonary Physiology (Osborne)
Renal Physiology
Concentration & Dilution of Urine
Gastrointestinal Physiology
Endocrinology
Reproductive Physiology
CAPS 303 – Human Physiology Laboratory: Honours (3 credits) Techniques and principle of human physiology. Restricted to students in CAPS & Pharmacology Honours.

Terms I and II

Restricted to students in CAP and Pharmacology Honours.

Laboratory:   Thursday 2:00 PM to 5:00 PM
Location: Copp Building Laboratories

Course Coordinator:   Dr. Sally Osborne
Telephone : 1.604.822.3421
Email: sally.osborne@ubc.ca
TAs:  Anna D’Sousa, Phillip Round

Schedule/ Course Info

TERM I
Informatics
Muscle Resting Potentials
Stretch/Hoffman Reflex
Conduction Velocity
Neuroanatomy
CNS Tutorial
Introduction to Surgical Techniques
Blood Pressure Analysis
TERM II
ECG
Spirometry
Cardiopulmonary Tutorial
Exercise & the Cardiopulmonary Response
Pharmacology
Regulation of Human Renal Function
Respiratory Renal Tutorial
Epithelial Active Transport
Human Oral Glucose Tolerance Test
CAPS 390 – Introduction to Microscopic Human Anatomy
(3 credits)
Instructor: Dr. Cal Roskelley
Prerequisite: one of the following courses:
BIOL 121 – Genetics, Evolution & Ecology
SCIE 001 – Science I Program
BIOL 200 – Cell Biology I: Structural Basis (recommended)
Download CAPS 390_Syllabus_2016
CAPS 391 – Introduction to Gross Human Anatomy (3 credits) Structure and function of body regions at the macroscopic level.

Term II (Winter) January to April

Prerequisite: Six credits of lower level biology courses.

Lectures and Labs: Monday, Wednesday, and Friday 10:00 AM to 11:00 AM.
Location: IRC II

Instructor: Dr. Majid Alimohammadi
Office: Room 1523, Life Sciences Centre
Telephone: 1.604.822.7545
Email :
maidad@mail.ubc.ca
Course Schedule and Topics 
Required Textbooks:
M & M Essential Anatomy, M. Alimohammadi, M. Doroudi, Pearson Publishing Company, 3rd. Edition.
Number of Lectures:12

CAPS 421 – Advanced Cellular & Molecular Physiology (3 credits) Recent advancements in cellular and molecular physiology that have revolutionized our understanding of cell function in health and disease.
Lectures:   Monday & Wednesday 2:00-4:00 pm, September – December  (D.H. Copp 2002)
Course Coordinators:   Dr. I. Robert Nabi & Dr. T. Michael Underhill
CAPS 422 – Mammalian Cardiovascular & Respiratory Physiology (3 credits) The control and integration of cardiopulmonary
function in mammals.
Lectures:   Tuesday & Thursday 8:00-10:00 am, September – December  (LSC 1510)
Course Coordinators:
  Dr. Sally Osborne and Dr. Ed Moore
Telephone : 1-604-822-3421 (Dr.Osborne)
Email: sally.osborne@ubc.ca / edmoore@mail.ubc.ca
Schedule/ Course Info
REVIEW ARTICLE
ECC ARTICLE
ECG’s and Arrhythmia handout
Excitation-Contraction Coupling and Regulation of Cardiac Contraction
CAPS 423 – Mammalian Renal & Gastrointestinal Physiology (3 credits) Control of mammalian renal and gastrointestinal systems.
Term I
Prerequiste: A cumulative average of 75% over at least 90 credits attempted in the first three years of a student’s program and a minimum mark of 75% in CAPS 301 or PHYL 301. Permission of the course director is also required.
Lectures:
  Tuesday & Thursday 2:00-4:00 pm, DH Copp 2002/2004 and LSC 1410
Course Coordinator:   Kenny Kwok, PhD
Office: Rm.3013 DH Copp Bldg, 2146 Health Sciences Mall
Telephone: 604-822-6228
Email: kenny.kwok@ubc.ca
Schedule / Course Info
Background Reading:   Selective Chapters of various textbook, Reviews and Journal articles.
Number of lectures: 23 two-hour lectures.
RENAL SECTION
Functional Anatomy and Circulation of the Kidney
Glomerular Filtration and Urinary Excretion
Renal Transports
Acid base balance
Fluid Compartments
Water Homeostasis
The Urinary Bladder
GASTROINTESTINAL SECTION
GI Tract Overview
GI Endocrinology
GI Innervation and Taste Perception
GI Innervation and Motility
Gastric Secretion
The Exocrine Pancreas
CAPS 424 – Mammalian Endocrinology (3 credits) Hormonal control of homeostatic, metabolic and reproductive function.
January – April
Lectures:  Tuesday, Thursday 2:00 PM to 4:00 PM
Location:  LSC 1510
Prerequisite: A cumulative average of 75% over at least 90 credits attempted in the first three years of a student’s program and a minimum mark of 75% in CAPS 301 or its equivalent. Permission of the course director is also required for all except Honours CAPS students.
Course Coordinator:   Dr. Susanne Clee
Office: Rm. 5352 Life Sciences Mall, 2350 Health Sciences Mall
Telephone: 1.604.827.4271
Email: susanne.clee@ubc.ca
Course Description
Schedule
Number of Lectures: 26
Required Textbook: None
This course is intended for Honours students in Physiology or other life sciences.
This course is eligible for Credit/D/Fail grading.
You must register in the course before you can select the Credit/D/Fail grading option.
Registered students will have access to a CAPS 424 web site on UBC Connect as of January 1 preceding the course. This is used for the posting of lecture notes and other relevant course material.
In addition to attending lectures, students will also participate in group-based mini-presentations of selected topics.
Course Assessment is based on mid-term and final examinations (90%) as well as the student presentations (10%).
Examinations are based upon lecture material only.
There are no recommended textbooks for the course.
TOPICS
Introduction (Baimbridge)
Membrane Receptors; Intracellular Signalling Pathways 1 & 2 (Luciani;)Steroid Receptors (Hammond)Endocrine control of transcription and development (Hoffman)Peptide Hormone Processing (Verchere)Hypothalamus/Pituitary Overview; Opioid peptide (Viau)Adrenal cortex; Adrenal medulla and the SNs;

Thyroid hormone; Calcium homeostasis (Baimbridge)

Regulation of Food Intake & Body Weight; Fat and Adipokines 1 & 2 (Clee) Pancreas Pt.1: Regulation of Insulin & Glucagon (Hoffman)

Pancreas Pts. 2 & 3: EnteroInsular Axis; Diabetes (Kieffer)

Reproductive Endocrinology 1, 2 &3; Endocrine systems & the life cycle (Hammond)

CAPS 426 – Physiological Basis of Central Nervous System Functions (3 credits) An integrated study of the structural and functional organization of the central nervous system with special emphasis on neurophysiological mechanisms.
January – April
Lectures:  Tuesday, Thursday 8:00-10:00am (Seminar Room, Copp Bldg)
Course Coordinator:   Dr. Kurt Haas
Office: BRC Room F162,
Tel: 604-822-9770
Email: kurt.haas@ubc.ca
Course Schedule and Topics
Prerequisites:   CAPS 301. Permission from the Department Head is also required.
CAPS 430 – Advanced Laboratory in Physiology (6 credits) A laboratory course giving training in the methods, techniques and use of instruments required for physiological investigation.

Term I & II

Prerequisite: CAPS 303 or PHYL 303 and the consent of the department are required and enrollment will be limited.

Laboratories:   Fridays 10:00 am – 5:00 pm
Location: Various

Course Coordinator:   Dr. Douglas Allan
Telephone: 1.604.827.5960
Email : doug.allan@ubc.ca
Office: Room 2401 Life Sciences Centre

This is a Laboratory Course for 4th Year Honours Physiology Students*

Number of Labs: 24

Course Schedule and Topics

TOPICS – Term I
Bioassay for blood pressure I (Baimbridge)Bioassay for blood pressure II (Baimbridge)Bioassay for blood pressure III (Baimbridge)Bioinformatics (Clee, Tanentzapf)Single cell electroporation (Haas)3-D Imaging of electroporated neurons (Haas)Human respiratory function (Osborne)RFLP/SNPs (Hammond)Bioinformatic analysis of synthetic genetic array data (Loewen)pH regulation of lipid metabolism (Loewen)Hypothesis, rationale and experimental planning (Allan)Immunohistochemistry techniques (Kieffer)
TOPICS – Term II
Insulin I: Glucose Regulation of Insulin Expression (Kieffer)Insulin II: OGTT (Kieffer)Insulin III: ELISA (Kieffer)Hypothesis, rationale and experimental planning (Allan)Live Cell Ca2+ Imaging (Johnson)Insulin IV: Viral Transfection (Kieffer)Electrophysiology introduction (Mason)Intracellular Recordings I (Mason)Intracellular Recordings II (Mason)Two-Electrode Voltage Clamp (Ahern)Drug block of ion channels (Kurata)
CAPS 448 – Directed Studies in Physiology (3-6 credits)
Course Director: Dr. Cal Roskelley (roskelly@mail.ubc.ca)
Description & Application
CAPS 449 – Graduating Essay  (6 credits) A two term research project with a Department faculty member, culminating in a written thesis and an oral presentation to faculty.
Contact:   Dr. Chris Loewen, Rm 2403 Life Sciences Center